There are two different ways of delivering the medication that is the synthesized form of the hormone progesterone during pregnancy. Progesterone is either delivered vaginally, in the form of a gel, pill, or suppository, or it’s delivered as a shot that’s administered by a doctor. The frequency that pregnant women who are at risk for preterm birth are prescribed to take progesterone is determined by which of these types of progesterone is prescribed.
Progesterone that’s delivered as a shot is administered weekly. On the other hand, progesterone that’s taken vaginally is prescribed to be taken daily, usually from around mid-way through the second trimester to near the end of the third.
Progesterone that’s given in the form of an injection is most often prescribed to women whose increased risk of preterm birth comes from having already had a spontaneous, preterm delivery in the past.
If you’re allergic to any of the ingredients in the branded progesterone shot, Makena, your healthcare provider will be able to talk to you about an alternative type of shot that’s put together at specific pharmacies.
Progesterone works to prevent preterm delivery by preventing contractions from starting. This means that some healthcare providers will stop prescribing progesterone some time around week 36, very near full-term gestation. Progesterone isn’t recommended for women who are carrying twins or other multiples.
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