The science of morning sickness

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Morning sickness is a real medical condition and very common. In fact, up to 85% of pregnant women experience morning sickness. So, what exactly is morning sickness and why does it happen?

What is morning sickness?

The medical term for morning sickness is “nausea and vomiting of pregnancy” (NVP). This name is a lot more accurate, since symptoms can strike at any time of day, not just in the morning. While NVP is most common during the first trimester, some women suffer throughout their entire pregnancy.

Morning sickness can include nausea with or without vomiting. As anyone who has felt nauseous can confirm, feeling like you need to vomit can make you just as miserable as actually vomiting.

What causes morning sickness?

Scientists are not sure exactly what causes morning sickness. The most popular theory is that morning sickness is linked to an increase in the hormone called human chorionic gonadotropin (hCG) during the first trimester of pregnancy, which is why NVP can be particularly intense during the first trimester.

How can morning sickness affect daily life?

Morning sickness can have a negative impact on almost every aspect of a pregnant woman’s life, both professional and personal. At work, trying to concentrate can be next to impossible when all you can focus on is the fastest route to the restroom or how quickly you can grab the nearest wastebasket. At home, an estimated 30 to 40% of pregnant women are unable to fully participate in family or social functions and in household activities due to their morning sickness symptoms. When you are nauseous and/or vomiting, just getting out of bed can be challenging!

How can you manage your symptoms?

For some women, simple changes in diet and lifestyle are enough to get their morning sickness symptoms under control. These changes can include having a snack before getting out of bed in the morning, eating small portions slowly and frequently, or consuming food and beverages that contain ginger. Avoiding environmental triggers like strong odors, flickering lights, and intense heat can also help.

Why is early treatment important?

When morning sickness strikes, early treatment can help prevent symptoms from getting worse. Morning sickness is a real medical condition and ignoring symptoms or trying to power through them can lead to weight loss and dehydration, which can sometimes result in hospitalization — and no one wants that! Which is why it is so important to tell your healthcare provider if you are experiencing morning sickness symptoms as soon as possible. Your provider will likely recommend that you try diet and lifestyle changes first. However, if these non-medicine treatments are not enough to get your symptoms under control, it may be time to ask if Bonjesta® is right for you.

Bonjesta® (doxylamine succinate and pyridoxine hydrochloride) is designed to be a fast-acting, long-lasting prescription medication that is FDA-approved for the treatment of morning sickness when diet and lifestyle changes do not work. Get back to feeling like yourself with Bonjesta®.

The most common side effect of Bonjesta is drowsiness. It has not been studied in women with hyperemesis gravidarum or children under age 18.

Learn more about Bonjesta

For US Residents Only.


  • Bonjesta® is a prescription medicine used to treat nausea & vomiting of pregnancy (NVP) in women who haven’t improved with change in diet/other non-medicine treatments.
  • It isn’t known if Bonjesta® is safe & effective in women with severe NVP (hyperemesis gravidarum). Women with this condition may need to be hospitalized.
  • It is not known if Bonjesta® is safe & effective in children under 18 years of age.



  • are allergic to doxylamine succinate, other ethanolamine derivative antihistamines, pyridoxine HCl or any ingredients in Bonjesta® (see Patient Information for list of ingredients);
  • take monoamine oxidase inhibitors (MAOIs) (ask your healthcare provider (HCP) or pharmacist if you aren’t sure if you take an MAOI).


  • The most common side effect of Bonjesta® is drowsiness.
  • Don’t drive, operate heavy machinery or do other activities that need your full attention unless your HCP says you can.
  • Don’t drink alcohol, or take other CNS depressants such as cough & cold medicines, certain pain medicines & medicines that help you sleep while taking Bonjesta®. Severe drowsiness can happen or become worse causing falls/accidents.
  • Bonjesta® may cause false positive urine drug screening test for methadone, opiates & PCP.

More safety information on Duchesnay USA encourages you to report negative side effects of prescription drugs to the FDA at or 1-800-FDA-1088.

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